Every Wednesday, at the moment. Maybe more often in the future, but I'm still pretty new to color comics.
Proooobably not? I'll be honest and say I'm not really going out of my way to make Promotion understandable without PF, but I don't think it'll be a major issue.
Clip Studio Pro for sketch/ink/colors and Photoshop CS2 for letters on a Cintiq Companion 2.